COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”

Coronavirus disease (COVID-19) outbreak has caused unprecedented global disruption since 2020. Approximately 238 million people are affected worldwide where the elderly succumb to mortality. Post-COVID syndrome and its side effects have popped up with several health hazards, such as macular degenera...

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Autores principales: Firoz, Arman, Talwar, Priti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080119/
https://www.ncbi.nlm.nih.gov/pubmed/35544976
http://dx.doi.org/10.1016/j.coph.2022.102231
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author Firoz, Arman
Talwar, Priti
author_facet Firoz, Arman
Talwar, Priti
author_sort Firoz, Arman
collection PubMed
description Coronavirus disease (COVID-19) outbreak has caused unprecedented global disruption since 2020. Approximately 238 million people are affected worldwide where the elderly succumb to mortality. Post-COVID syndrome and its side effects have popped up with several health hazards, such as macular degeneration and vision loss. It thus necessitates better medical care and management of our dietary practices. Natural flavonoids have been included in traditional medicine and have also been used safely against COVID-19 and several other diseases. Kaempferol is an essential flavonoid that has been demonstrated to influence several vital cellular signaling pathways involved in apoptosis, angiogenesis, inflammation, and autophagy. In this review, we emphasize the plausible regulatory effects of Kaempferol on hallmarks of COVID-19 and macular degeneration.
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spelling pubmed-90801192022-05-09 COVID-19 and retinal degenerative diseases: Promising link “Kaempferol” Firoz, Arman Talwar, Priti Curr Opin Pharmacol Article Coronavirus disease (COVID-19) outbreak has caused unprecedented global disruption since 2020. Approximately 238 million people are affected worldwide where the elderly succumb to mortality. Post-COVID syndrome and its side effects have popped up with several health hazards, such as macular degeneration and vision loss. It thus necessitates better medical care and management of our dietary practices. Natural flavonoids have been included in traditional medicine and have also been used safely against COVID-19 and several other diseases. Kaempferol is an essential flavonoid that has been demonstrated to influence several vital cellular signaling pathways involved in apoptosis, angiogenesis, inflammation, and autophagy. In this review, we emphasize the plausible regulatory effects of Kaempferol on hallmarks of COVID-19 and macular degeneration. Elsevier Ltd. 2022-06 2022-04-14 /pmc/articles/PMC9080119/ /pubmed/35544976 http://dx.doi.org/10.1016/j.coph.2022.102231 Text en © 2022 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Firoz, Arman
Talwar, Priti
COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”
title COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”
title_full COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”
title_fullStr COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”
title_full_unstemmed COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”
title_short COVID-19 and retinal degenerative diseases: Promising link “Kaempferol”
title_sort covid-19 and retinal degenerative diseases: promising link “kaempferol”
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080119/
https://www.ncbi.nlm.nih.gov/pubmed/35544976
http://dx.doi.org/10.1016/j.coph.2022.102231
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