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Single-cell genomics identifies distinct B1 cell developmental pathways and reveals aging-related changes in the B-cell receptor repertoire

BACKGROUND: B1 cells are self-renewing innate-like B lymphocytes that provide the first line of defense against pathogens. B1 cells primarily reside in the peritoneal cavity and are known to originate from various fetal tissues, yet their developmental pathways and the mechanisms underlying maintena...

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Detalles Bibliográficos
Autores principales:	Luo, Yao, Wang, Jing, Li, Kairui, Li, Mingxia, Xu, Shasha, Liu, Xingjie, Zhang, Zhiwei, Xu, Xiang, Zhang, Yu, Pan, Jiawei, Liu, Pengtao, Gao, Shaorong, Miao, Zhichao, Yu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080186/ https://www.ncbi.nlm.nih.gov/pubmed/35526067 http://dx.doi.org/10.1186/s13578-022-00795-6

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