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The effect of TGF-β(1) polymorphisms on pulmonary disease progression in patients with cystic fibrosis

BACKGROUND: Transforming Growth Factor-β(1) (TGF-β(1)) is a genetic modifier in patients with cystic fibrosis (CF). Several single nucleotide polymorphisms (SNPs) of TGF-β(1) are associated with neutrophilic inflammation, lung fibrosis and loss of pulmonary function. AIM: The aim of this study was t...

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Detalles Bibliográficos
Autores principales: Trojan, T., Alejandre Alcazar, Miguel A., Fink, G., Thomassen, J. C., Maessenhausen, M. V., Rietschel, E., Schneider, P. M., van Koningsbruggen-Rietschel, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080196/
https://www.ncbi.nlm.nih.gov/pubmed/35525938
http://dx.doi.org/10.1186/s12890-022-01977-1

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