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Influence of cytochrome P450 and glutathione S transferase polymorphisms on response to nilotinib therapy among chronic myeloidleukemia patients from Pakistan

BACKGROUND: Cytochrome P450 (CYP) and glutathione S transferases (GSTs) are important biotransforming enzymes responsible for detoxification of anticancer drugs and carcinogens. Polymorphisms in these enzymes may greatly influence the susceptibility to CML and overall efficacy of tyrosine kinase inh...

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Detalles Bibliográficos
Autores principales:	Mukry, Samina Naz, Shahni, Aneeta, Zaidi, Uzma, Sultan Shamsi, Tahir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080200/ https://www.ncbi.nlm.nih.gov/pubmed/35527244 http://dx.doi.org/10.1186/s12885-022-09605-1

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