Thymoquinone Induces Downregulation of BCR-ABL/JAK/STAT Pathway and Apoptosis in K562 Leukemia Cells

OBJECTIVE: BCR ABL oncogene encodes the BCR-ABL chimeric protein, which is a constitutively activated non-receptor tyrosine kinase. The BCR-ABL oncoprotein is a key molecular basis for the pathogenesis of chronic myeloid leukemia (CML) via activation of several downstream signaling pathways includin...

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Detalles Bibliográficos
Autores principales: Al-Rawashde, Futoon Abedrabbu, Taib, Wan Rohani Wan, Ismail, Imilia, Johan, Muhammad Farid, Al-wajeeh, Abdullah Saleh, Al-Jamal, Hamid Ali Nagi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080382/
https://www.ncbi.nlm.nih.gov/pubmed/34967577
http://dx.doi.org/10.31557/APJCP.2021.22.12.3959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080382/
https://www.ncbi.nlm.nih.gov/pubmed/34967577
http://dx.doi.org/10.31557/APJCP.2021.22.12.3959

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