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Direct speciation methods to quantify catalytically active species of AlCl(3) in glucose isomerization

While homogeneous metal halides have been shown to catalyze glucose to fructose isomerization, direct experimental evidence in support of the catalytically active species remains elusive. Here, we integrate direct speciation methods with kinetics to provide strong evidence for the active species of...

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Autores principales: Norton, Angela M., Nguyen, Hannah, Xiao, Nicholas L., Vlachos, Dionisios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080408/
https://www.ncbi.nlm.nih.gov/pubmed/35539252
http://dx.doi.org/10.1039/c8ra03088j
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author Norton, Angela M.
Nguyen, Hannah
Xiao, Nicholas L.
Vlachos, Dionisios G.
author_facet Norton, Angela M.
Nguyen, Hannah
Xiao, Nicholas L.
Vlachos, Dionisios G.
author_sort Norton, Angela M.
collection PubMed
description While homogeneous metal halides have been shown to catalyze glucose to fructose isomerization, direct experimental evidence in support of the catalytically active species remains elusive. Here, we integrate direct speciation methods with kinetics to provide strong evidence for the active species of AlCl(3) in glucose–fructose isomerization in water. We investigate the effect of Lewis (AlCl(3)) and Brønsted (HCl) acids on aluminum hydrolysis and glucose conversion. We demonstrate the interplay between the acids using the Optimum Logic Inc. speciation model (OLI software). We measure aqueous aluminum species and protons through in situ and ex situ(27)Al quantitative nuclear magnetic resonance (qNMR) and pH measurements, respectively, and quantify aluminum nanoparticles through a combination of inductively coupled plasma-mass spectrometry (ICP-MS), dynamic light scattering (DLS), and ultrafiltration. Direct speciation measurements correlated with the glucose isomerization rate indicate that the hydrolyzed Al(iii) complex [Al(H(2)O)(4)(OH)(2)](1+) is the active species in glucose isomerization.
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spelling pubmed-90804082022-05-09 Direct speciation methods to quantify catalytically active species of AlCl(3) in glucose isomerization Norton, Angela M. Nguyen, Hannah Xiao, Nicholas L. Vlachos, Dionisios G. RSC Adv Chemistry While homogeneous metal halides have been shown to catalyze glucose to fructose isomerization, direct experimental evidence in support of the catalytically active species remains elusive. Here, we integrate direct speciation methods with kinetics to provide strong evidence for the active species of AlCl(3) in glucose–fructose isomerization in water. We investigate the effect of Lewis (AlCl(3)) and Brønsted (HCl) acids on aluminum hydrolysis and glucose conversion. We demonstrate the interplay between the acids using the Optimum Logic Inc. speciation model (OLI software). We measure aqueous aluminum species and protons through in situ and ex situ(27)Al quantitative nuclear magnetic resonance (qNMR) and pH measurements, respectively, and quantify aluminum nanoparticles through a combination of inductively coupled plasma-mass spectrometry (ICP-MS), dynamic light scattering (DLS), and ultrafiltration. Direct speciation measurements correlated with the glucose isomerization rate indicate that the hydrolyzed Al(iii) complex [Al(H(2)O)(4)(OH)(2)](1+) is the active species in glucose isomerization. The Royal Society of Chemistry 2018-05-09 /pmc/articles/PMC9080408/ /pubmed/35539252 http://dx.doi.org/10.1039/c8ra03088j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Norton, Angela M.
Nguyen, Hannah
Xiao, Nicholas L.
Vlachos, Dionisios G.
Direct speciation methods to quantify catalytically active species of AlCl(3) in glucose isomerization
title Direct speciation methods to quantify catalytically active species of AlCl(3) in glucose isomerization
title_full Direct speciation methods to quantify catalytically active species of AlCl(3) in glucose isomerization
title_fullStr Direct speciation methods to quantify catalytically active species of AlCl(3) in glucose isomerization
title_full_unstemmed Direct speciation methods to quantify catalytically active species of AlCl(3) in glucose isomerization
title_short Direct speciation methods to quantify catalytically active species of AlCl(3) in glucose isomerization
title_sort direct speciation methods to quantify catalytically active species of alcl(3) in glucose isomerization
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080408/
https://www.ncbi.nlm.nih.gov/pubmed/35539252
http://dx.doi.org/10.1039/c8ra03088j
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