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Design, synthesis and biological evaluation of N-arylsulfonyl carbazoles as novel anticancer agents

In this work, a set of structurally diverse synthetic carbazoles was screened for their anticancer activities. According to structure–activity relationship studies, carbazoles with an N-substituted sulfonyl group exhibited better anticancer activity. Moreover, compound 8h was discovered to show the...

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Detalles Bibliográficos
Autores principales: You, Xin, Zhu, Daqian, Lu, Wenhua, Sun, Yichen, Qiao, Shuang, Luo, Bingling, Du, Yongliang, Pi, Rongbiao, Hu, Yumin, Huang, Peng, Wen, Shijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080423/
https://www.ncbi.nlm.nih.gov/pubmed/35539273
http://dx.doi.org/10.1039/c8ra02939c