Design, synthesis, and biological evaluation of AV6 derivatives as novel dual reactivators of latent HIV-1

The “shock and kill” strategy might be a promising therapeutic approach for HIV/AIDS due to the existence of latent viral reservoirs. A major challenge of the “shock and kill” strategy arises from the general lack of clinically effective latency-reversing agents (LRAs). The 2-methylquinoline derivat...

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Detalles Bibliográficos
Autores principales: Ao, Mingtao, Pan, Zhenrui, Qian, Yuqing, Tang, Bowen, Feng, Zeming, Fang, Hua, Wu, Zhen, Chen, Jingwei, Xue, Yuhua, Fang, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080425/
https://www.ncbi.nlm.nih.gov/pubmed/35539279
http://dx.doi.org/10.1039/c8ra01216d

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