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Synthesis and biological evaluation of 2-aryl-benzimidazole derivatives of dehydroabietic acid as novel tubulin polymerization inhibitors

A series of novel 2-aryl-benzimidazole derivatives of dehydroabietic acid were synthesized and characterized by IR, (1)H NMR, (13)C NMR, MS and elemental analyses. All the target compounds were evaluated for their in vitro cytotoxic activity against SMMC-7721, MDA-MB-231, HeLa and CT-26 cancer cell...

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Detalles Bibliográficos
Autores principales:	Miao, Ting-Ting, Tao, Xu-Bing, Li, Dong-Dong, Chen, Hao, Jin, Xiao-Yan, Geng, Yi, Wang, Shi-Fa, Gu, Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080489/ https://www.ncbi.nlm.nih.gov/pubmed/35539265 http://dx.doi.org/10.1039/c8ra02078g

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