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Molecular basis of rutin inhibition of protein disulfide isomerase (PDI) by combined in silico and experimental methods

Protein disulfide isomerase (PDI) is a founding member of the thiol isomerase family, and is recently found to play critical roles in thrombus formation. The development of effective PDI inhibitors is of great significance, and attracts strong interest. We previously showed that rutin bound directly...

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Detalles Bibliográficos
Autores principales:	Wang, Xu, Xue, Guangpu, Song, Meiru, Xu, Peng, Chen, Dan, Yuan, Cai, Lin, Lin, Flaumenhaft, Robert, Li, Jinyu, Huang, Mingdong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080521/ https://www.ncbi.nlm.nih.gov/pubmed/35541126 http://dx.doi.org/10.1039/c8ra02683a

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