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Recent review of the effect of nanomaterials on stem cells
The field of stem-cell-therapy offers considerable promise as a means of delivering new treatments for a wide range of diseases. Recent progress in nanotechnology has stimulated the development of multifunctional nanomaterials (NMs) for stem-cell-therapy. Several clinical trials based on the use of...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080527/ https://www.ncbi.nlm.nih.gov/pubmed/35542058 http://dx.doi.org/10.1039/c8ra02424c |
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author | Zhou, Xu Yuan, Long Wu, Chengzhou Cheng chen, Luo, Gaoxing Deng, Jun Mao, Zhengwei |
author_facet | Zhou, Xu Yuan, Long Wu, Chengzhou Cheng chen, Luo, Gaoxing Deng, Jun Mao, Zhengwei |
author_sort | Zhou, Xu |
collection | PubMed |
description | The field of stem-cell-therapy offers considerable promise as a means of delivering new treatments for a wide range of diseases. Recent progress in nanotechnology has stimulated the development of multifunctional nanomaterials (NMs) for stem-cell-therapy. Several clinical trials based on the use of NMs are currently underway for stem-cell-therapy purposes, such as drug/gene delivery and imaging. However, the interactions between NMs and stem cells are far from being completed, and the effects of the NMs on cellular behavior need critical evaluation. In this review, the interactions between several types of mostly used NMs and stem cells, and their associated possible mechanisms are systematically discussed, with specific emphasis on the possible differentiation effects induced by NMs. It is expected that the enhanced understanding of NM-stem cell interactions will facilitate biomaterial design for stem-cell-therapy and regenerative medicine applications. |
format | Online Article Text |
id | pubmed-9080527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-90805272022-05-09 Recent review of the effect of nanomaterials on stem cells Zhou, Xu Yuan, Long Wu, Chengzhou Cheng chen, Luo, Gaoxing Deng, Jun Mao, Zhengwei RSC Adv Chemistry The field of stem-cell-therapy offers considerable promise as a means of delivering new treatments for a wide range of diseases. Recent progress in nanotechnology has stimulated the development of multifunctional nanomaterials (NMs) for stem-cell-therapy. Several clinical trials based on the use of NMs are currently underway for stem-cell-therapy purposes, such as drug/gene delivery and imaging. However, the interactions between NMs and stem cells are far from being completed, and the effects of the NMs on cellular behavior need critical evaluation. In this review, the interactions between several types of mostly used NMs and stem cells, and their associated possible mechanisms are systematically discussed, with specific emphasis on the possible differentiation effects induced by NMs. It is expected that the enhanced understanding of NM-stem cell interactions will facilitate biomaterial design for stem-cell-therapy and regenerative medicine applications. The Royal Society of Chemistry 2018-05-15 /pmc/articles/PMC9080527/ /pubmed/35542058 http://dx.doi.org/10.1039/c8ra02424c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Zhou, Xu Yuan, Long Wu, Chengzhou Cheng chen, Luo, Gaoxing Deng, Jun Mao, Zhengwei Recent review of the effect of nanomaterials on stem cells |
title | Recent review of the effect of nanomaterials on stem cells |
title_full | Recent review of the effect of nanomaterials on stem cells |
title_fullStr | Recent review of the effect of nanomaterials on stem cells |
title_full_unstemmed | Recent review of the effect of nanomaterials on stem cells |
title_short | Recent review of the effect of nanomaterials on stem cells |
title_sort | recent review of the effect of nanomaterials on stem cells |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080527/ https://www.ncbi.nlm.nih.gov/pubmed/35542058 http://dx.doi.org/10.1039/c8ra02424c |
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