Novel caged luciferin derivatives can prolong bioluminescence imaging in vitro and in vivo

Based on N-cyclobutylaminoluciferin (cybLuc), a set of high and efficient caged bioluminescent derivatives (Clucs) as firefly luciferase pro-substrates has been developed herein. After careful examination, these molecules exhibited low cytotoxicity and prolonged bioluminescence imaging up to 6 h in...

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Detalles Bibliográficos
Autores principales: Zhang, Chaochao, Yuan, Mingliang, Han, Guangxi, Gao, Yuqi, Tang, Chunchao, Li, Xiang, Du, Lupei, Li, Minyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080648/
https://www.ncbi.nlm.nih.gov/pubmed/35540985
http://dx.doi.org/10.1039/c8ra02312c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080648/
https://www.ncbi.nlm.nih.gov/pubmed/35540985
http://dx.doi.org/10.1039/c8ra02312c

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