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Early stage release control of an anticancer drug by drug-polymer miscibility in a hydrophobic fiber-based drug delivery system
The drug release profiles of doxorubicin-loaded electrospun fiber mats were investigated with regard to drug-polymer miscibility, fiber wettability and degradability. Doxorubicin in hydrophilic form (Dox-HCl) and hydrophobic free base form (Dox-base) was employed as model drugs, and an aliphatic pol...
Autores principales: | Yuan, Yue, Choi, Kyoungju, Choi, Seong-O, Kim, Jooyoun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080684/ https://www.ncbi.nlm.nih.gov/pubmed/35540999 http://dx.doi.org/10.1039/c8ra01467a |
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