Synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition

Curcumin has been transformed to several diversely substituted bis-pyrrolizidino/thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via a sequential azomethine ylide cycloaddition reaction using isatins/acenaphthoquinone and proline/thioproline as the reagents. The products were separated via ex...

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Autores principales: Singh, Meenakshi, Hazra, Abhijit, Bharitkar, Yogesh P., Kalia, Ritu, Sahoo, Ashutosh, Saha, Sneha, Ravichandiran, V., Ghosh, Shekhar, Mondal, Nirup B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080697/
https://www.ncbi.nlm.nih.gov/pubmed/35539652
http://dx.doi.org/10.1039/c8ra02725k
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author Singh, Meenakshi
Hazra, Abhijit
Bharitkar, Yogesh P.
Kalia, Ritu
Sahoo, Ashutosh
Saha, Sneha
Ravichandiran, V.
Ghosh, Shekhar
Mondal, Nirup B.
author_facet Singh, Meenakshi
Hazra, Abhijit
Bharitkar, Yogesh P.
Kalia, Ritu
Sahoo, Ashutosh
Saha, Sneha
Ravichandiran, V.
Ghosh, Shekhar
Mondal, Nirup B.
author_sort Singh, Meenakshi
collection PubMed
description Curcumin has been transformed to several diversely substituted bis-pyrrolizidino/thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via a sequential azomethine ylide cycloaddition reaction using isatins/acenaphthoquinone and proline/thioproline as the reagents. The products were separated via extensive chromatography and characterized by 1D/2D NMR and HRMS analysis.
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spelling pubmed-90806972022-05-09 Synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition Singh, Meenakshi Hazra, Abhijit Bharitkar, Yogesh P. Kalia, Ritu Sahoo, Ashutosh Saha, Sneha Ravichandiran, V. Ghosh, Shekhar Mondal, Nirup B. RSC Adv Chemistry Curcumin has been transformed to several diversely substituted bis-pyrrolizidino/thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via a sequential azomethine ylide cycloaddition reaction using isatins/acenaphthoquinone and proline/thioproline as the reagents. The products were separated via extensive chromatography and characterized by 1D/2D NMR and HRMS analysis. The Royal Society of Chemistry 2018-05-23 /pmc/articles/PMC9080697/ /pubmed/35539652 http://dx.doi.org/10.1039/c8ra02725k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Singh, Meenakshi
Hazra, Abhijit
Bharitkar, Yogesh P.
Kalia, Ritu
Sahoo, Ashutosh
Saha, Sneha
Ravichandiran, V.
Ghosh, Shekhar
Mondal, Nirup B.
Synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition
title Synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition
title_full Synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition
title_fullStr Synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition
title_full_unstemmed Synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition
title_short Synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition
title_sort synthesis of diversely substituted bis-pyrrolizidino/ thiopyrrolizidino oxindolo/acenaphthyleno curcuminoids via sequential azomethine ylide cycloaddition
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080697/
https://www.ncbi.nlm.nih.gov/pubmed/35539652
http://dx.doi.org/10.1039/c8ra02725k
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