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Chiral ruthenium(ii) complex as potent radiosensitizer of (125)I through DNA-damage-mediated apoptosis

A chiral ruthenium(ii) complex, Λ-[Ru(bpy)(2)(o-tFMPIP)] (ClO(4))(2) (o-tFMPIP = 2′-trifluoromethylphenyl) imidazo [4,5-f][1,10]phenanthroline, was prepared and evaluated for its enhancement of the radiosensitivity of (125)I seeds. The synthetic Ru(ii) complex, LR042, effectively enhanced growth inh...

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Detalles Bibliográficos
Autores principales:	Bai, Mingjun, Zeng, Zhaolin, Li, Li, Wu, Qiong, Zhang, Yanyang, Pan, Tao, Mu, Luwen, Zhu, Duo, Guan, Shouhai, Xie, Qiang, Mei, Wenjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080800/ https://www.ncbi.nlm.nih.gov/pubmed/35542349 http://dx.doi.org/10.1039/c8ra03383h

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