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Amplifying fluorescence signal contrast of aptamer-modified microspheres inspired by whispering-gallery mode lasing

We propose a new sensor design that maximizes fluorescence contrast, inspired by whispering-gallery mode lasing (WGM). Aptamer-modified glass microspheres (cf. 1–38 μm) and thrombin are used as a model sensory cavity and target protein, respectively. Two types of microsphere are prepared to compare...

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Detalles Bibliográficos
Autores principales: Kim, Sooyeon, Kuroda, Ayaka, Fujitsuka, Mamoru, Majima, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080894/
https://www.ncbi.nlm.nih.gov/pubmed/35542363
http://dx.doi.org/10.1039/c8ra03192d