Controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles

A series of amphiphilic PDMAEMA–SS–PCL chains with variable ratios of hydrophilic poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) to hydrophobic poly(ε-caprolactone) (PCL) were prepared via ring-opening polymerization, in which the two different moieties were linked via a disulfide bond with red...

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Autores principales: Zhou, Xiaoteng, Li, Lingxiao, Qin, He, Ning, Bo, Li, Junpei, Kan, Chengyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080933/
https://www.ncbi.nlm.nih.gov/pubmed/35539922
http://dx.doi.org/10.1039/c8ra03374a
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author Zhou, Xiaoteng
Li, Lingxiao
Qin, He
Ning, Bo
Li, Junpei
Kan, Chengyou
author_facet Zhou, Xiaoteng
Li, Lingxiao
Qin, He
Ning, Bo
Li, Junpei
Kan, Chengyou
author_sort Zhou, Xiaoteng
collection PubMed
description A series of amphiphilic PDMAEMA–SS–PCL chains with variable ratios of hydrophilic poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) to hydrophobic poly(ε-caprolactone) (PCL) were prepared via ring-opening polymerization, in which the two different moieties were linked via a disulfide bond with reduction responsiveness. After cross-linking by the photodegradable o-nitrobenzyl linkage, the amphiphilic chains could self-assemble into microspheres, branched cylindrical micelles and vesicles, which were responsive to the reduction agent dl-dithiothreitol and UV light irradiation through different mechanisms.
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spelling pubmed-90809332022-05-09 Controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles Zhou, Xiaoteng Li, Lingxiao Qin, He Ning, Bo Li, Junpei Kan, Chengyou RSC Adv Chemistry A series of amphiphilic PDMAEMA–SS–PCL chains with variable ratios of hydrophilic poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) to hydrophobic poly(ε-caprolactone) (PCL) were prepared via ring-opening polymerization, in which the two different moieties were linked via a disulfide bond with reduction responsiveness. After cross-linking by the photodegradable o-nitrobenzyl linkage, the amphiphilic chains could self-assemble into microspheres, branched cylindrical micelles and vesicles, which were responsive to the reduction agent dl-dithiothreitol and UV light irradiation through different mechanisms. The Royal Society of Chemistry 2018-06-13 /pmc/articles/PMC9080933/ /pubmed/35539922 http://dx.doi.org/10.1039/c8ra03374a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Zhou, Xiaoteng
Li, Lingxiao
Qin, He
Ning, Bo
Li, Junpei
Kan, Chengyou
Controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles
title Controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles
title_full Controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles
title_fullStr Controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles
title_full_unstemmed Controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles
title_short Controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles
title_sort controlled self-assembly into diverse stimuli-responsive microstructures: from microspheres to branched cylindrical micelles and vesicles
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080933/
https://www.ncbi.nlm.nih.gov/pubmed/35539922
http://dx.doi.org/10.1039/c8ra03374a
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