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Survival motor neuron protein deficiency alters microglia reactivity

Survival motor neuron (SMN) protein deficiency results in loss of alpha motor neurons and subsequent muscle atrophy in patients with spinal muscular atrophy (SMA). Reactive microglia have been reported in SMA mice and depleting microglia rescues the number of proprioceptive synapses, suggesting a ro...

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Detalles Bibliográficos
Autores principales: Khayrullina, Guzal, Alipio‐Gloria, Zaida A., Deguise, Marc‐Olivier, Gagnon, Sabrina, Chehade, Lucia, Stinson, Matthew, Belous, Natalya, Bergman, Elizabeth M., Lischka, Fritz W., Rotty, Jeremy, Dalgard, Clifton L., Kothary, Rashmi, Johnson, Kristen A., Burnett, Barrington G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081169/
https://www.ncbi.nlm.nih.gov/pubmed/35373853
http://dx.doi.org/10.1002/glia.24177