Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones

A simple, mild, catalytic and efficient method for the straightforward synthesis of an interesting class of 2-aryl/alkyl-substituted-3-indolyl quinones in good to high yields is reported for the first time. This atom-efficient method proceeds via copper-catalyzed one-pot sequential intramolecular hy...

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Detalles Bibliográficos
Autores principales: Jillella, Raveendra, Oh, Chang Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081399/
https://www.ncbi.nlm.nih.gov/pubmed/35541709
http://dx.doi.org/10.1039/c8ra03712d
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author Jillella, Raveendra
Oh, Chang Ho
author_facet Jillella, Raveendra
Oh, Chang Ho
author_sort Jillella, Raveendra
collection PubMed
description A simple, mild, catalytic and efficient method for the straightforward synthesis of an interesting class of 2-aryl/alkyl-substituted-3-indolyl quinones in good to high yields is reported for the first time. This atom-efficient method proceeds via copper-catalyzed one-pot sequential intramolecular hydroamination (C–N bond formation) of 2-alkynylanilines followed by oxidative C–C coupling with benzoquinones.
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spelling pubmed-90813992022-05-09 Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones Jillella, Raveendra Oh, Chang Ho RSC Adv Chemistry A simple, mild, catalytic and efficient method for the straightforward synthesis of an interesting class of 2-aryl/alkyl-substituted-3-indolyl quinones in good to high yields is reported for the first time. This atom-efficient method proceeds via copper-catalyzed one-pot sequential intramolecular hydroamination (C–N bond formation) of 2-alkynylanilines followed by oxidative C–C coupling with benzoquinones. The Royal Society of Chemistry 2018-06-15 /pmc/articles/PMC9081399/ /pubmed/35541709 http://dx.doi.org/10.1039/c8ra03712d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Jillella, Raveendra
Oh, Chang Ho
Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones
title Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones
title_full Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones
title_fullStr Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones
title_full_unstemmed Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones
title_short Copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones
title_sort copper-catalyzed tandem reaction of 2-alkynylanilines with benzoquinones: efficient access to 3-indolylquinones
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081399/
https://www.ncbi.nlm.nih.gov/pubmed/35541709
http://dx.doi.org/10.1039/c8ra03712d
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AT ohchangho coppercatalyzedtandemreactionof2alkynylanilineswithbenzoquinonesefficientaccessto3indolylquinones

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