Genetically Determined Lifestyle and Cardiometabolic Risk Factors Mediate the Association of Genetically Predicted Age at Menarche With Genetic Predisposition to Myocardial Infarction: A Two-Step, Two-Sample Mendelian Randomization Study

BACKGROUND: Observational studies have shown an association between early age at menarche (AAM) and myocardial infarction (MI) with recorded cases. In this Mendelian randomization (MR) study, we used large amounts of summary data from genome-wide association studies (GWASs) to further estimate the a...

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Detalles Bibliográficos
Autores principales: Zheng, Jilin, Chen, Ken, Huang, Tao, Shao, Chunli, Li, Ping, Wang, Jingjia, Wang, Wenyao, Zhang, Kuo, Meng, Xiangbin, Gao, Jun, Wang, Xuliang, Liu, Yupeng, Song, Jingjing, Dong, Eran, Tang, Yi-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081496/
https://www.ncbi.nlm.nih.gov/pubmed/35548428
http://dx.doi.org/10.3389/fcvm.2022.821068

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