Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes

Iodine-promoted three-component synthesis of substituted β-amino sulfides has been developed starting from a propargyl ester, aliphatic secondary amine, and disulfide. This protocol provides a step-economic and highly regioselective entry to trisubstituted olefins with good substrate scope and funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Fuhong, Wang, Dahan, Yuan, Shanshan, Huang, Huawen, Deng, Guo-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081554/
https://www.ncbi.nlm.nih.gov/pubmed/35540165
http://dx.doi.org/10.1039/c8ra04374d
_version_ 1784703010808528896
author Xiao, Fuhong
Wang, Dahan
Yuan, Shanshan
Huang, Huawen
Deng, Guo-Jun
author_facet Xiao, Fuhong
Wang, Dahan
Yuan, Shanshan
Huang, Huawen
Deng, Guo-Jun
author_sort Xiao, Fuhong
collection PubMed
description Iodine-promoted three-component synthesis of substituted β-amino sulfides has been developed starting from a propargyl ester, aliphatic secondary amine, and disulfide. This protocol provides a step-economic and highly regioselective entry to trisubstituted olefins with good substrate scope and functional group tolerance.
format Online
Article
Text
id pubmed-9081554
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90815542022-05-09 Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes Xiao, Fuhong Wang, Dahan Yuan, Shanshan Huang, Huawen Deng, Guo-Jun RSC Adv Chemistry Iodine-promoted three-component synthesis of substituted β-amino sulfides has been developed starting from a propargyl ester, aliphatic secondary amine, and disulfide. This protocol provides a step-economic and highly regioselective entry to trisubstituted olefins with good substrate scope and functional group tolerance. The Royal Society of Chemistry 2018-06-27 /pmc/articles/PMC9081554/ /pubmed/35540165 http://dx.doi.org/10.1039/c8ra04374d Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Xiao, Fuhong
Wang, Dahan
Yuan, Shanshan
Huang, Huawen
Deng, Guo-Jun
Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes
title Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes
title_full Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes
title_fullStr Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes
title_full_unstemmed Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes
title_short Iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes
title_sort iodine-promoted stereoselective amidosulfenylation of electron-deficient alkynes
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081554/
https://www.ncbi.nlm.nih.gov/pubmed/35540165
http://dx.doi.org/10.1039/c8ra04374d
work_keys_str_mv AT xiaofuhong iodinepromotedstereoselectiveamidosulfenylationofelectrondeficientalkynes
AT wangdahan iodinepromotedstereoselectiveamidosulfenylationofelectrondeficientalkynes
AT yuanshanshan iodinepromotedstereoselectiveamidosulfenylationofelectrondeficientalkynes
AT huanghuawen iodinepromotedstereoselectiveamidosulfenylationofelectrondeficientalkynes
AT dengguojun iodinepromotedstereoselectiveamidosulfenylationofelectrondeficientalkynes

Ejemplares similares