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The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions

An iodine-mediated decarboxylative cyclization was developed from α-amino acids and 2-methyl quinolines under metal-free conditions, affording a variety of imidazo[1,5-a]quinolines with moderate to good yields.

Detalles Bibliográficos
Autores principales: Yan, Zicong, Wan, Changfeng, Yang, Yu, Zha, Zhenggen, Wang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081590/
https://www.ncbi.nlm.nih.gov/pubmed/35540158
http://dx.doi.org/10.1039/c8ra03786h
Descripción
Sumario:An iodine-mediated decarboxylative cyclization was developed from α-amino acids and 2-methyl quinolines under metal-free conditions, affording a variety of imidazo[1,5-a]quinolines with moderate to good yields.