The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions

An iodine-mediated decarboxylative cyclization was developed from α-amino acids and 2-methyl quinolines under metal-free conditions, affording a variety of imidazo[1,5-a]quinolines with moderate to good yields.

Detalles Bibliográficos
Autores principales: Yan, Zicong, Wan, Changfeng, Yang, Yu, Zha, Zhenggen, Wang, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081590/
https://www.ncbi.nlm.nih.gov/pubmed/35540158
http://dx.doi.org/10.1039/c8ra03786h
_version_ 1784703019705696256
author Yan, Zicong
Wan, Changfeng
Yang, Yu
Zha, Zhenggen
Wang, Zhiyong
author_facet Yan, Zicong
Wan, Changfeng
Yang, Yu
Zha, Zhenggen
Wang, Zhiyong
author_sort Yan, Zicong
collection PubMed
description An iodine-mediated decarboxylative cyclization was developed from α-amino acids and 2-methyl quinolines under metal-free conditions, affording a variety of imidazo[1,5-a]quinolines with moderate to good yields.
format Online
Article
Text
id pubmed-9081590
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90815902022-05-09 The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions Yan, Zicong Wan, Changfeng Yang, Yu Zha, Zhenggen Wang, Zhiyong RSC Adv Chemistry An iodine-mediated decarboxylative cyclization was developed from α-amino acids and 2-methyl quinolines under metal-free conditions, affording a variety of imidazo[1,5-a]quinolines with moderate to good yields. The Royal Society of Chemistry 2018-06-25 /pmc/articles/PMC9081590/ /pubmed/35540158 http://dx.doi.org/10.1039/c8ra03786h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Yan, Zicong
Wan, Changfeng
Yang, Yu
Zha, Zhenggen
Wang, Zhiyong
The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions
title The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions
title_full The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions
title_fullStr The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions
title_full_unstemmed The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions
title_short The synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions
title_sort synthesis of imidazo[1,5-a]quinolines via a decarboxylative cyclization under metal-free conditions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081590/
https://www.ncbi.nlm.nih.gov/pubmed/35540158
http://dx.doi.org/10.1039/c8ra03786h
work_keys_str_mv AT yanzicong thesynthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT wanchangfeng thesynthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT yangyu thesynthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT zhazhenggen thesynthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT wangzhiyong thesynthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT yanzicong synthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT wanchangfeng synthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT yangyu synthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT zhazhenggen synthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions
AT wangzhiyong synthesisofimidazo15aquinolinesviaadecarboxylativecyclizationundermetalfreeconditions

Ejemplares similares