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The Interplay Between Biliary Occlusion and Liver Regeneration: Repeated Regeneration Stimuli Restore Biliary Drainage by Promoting Hepatobiliary Remodeling in a Rat Model

BACKGROUND AND AIMS: Patients with malignant biliary obstruction do not seem to benefit from “two-stage hepatectomy” due to an impairment of liver regeneration. We designed a novel model of “repeated regeneration stimuli” in rats mimicking a “two-stage hepatectomy” with selective or complete biliary...

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Detalles Bibliográficos
Autores principales: Richter, Beate, Sänger, Constanze, Mussbach, Franziska, Scheuerlein, Hubert, Settmacher, Utz, Dahmen, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081651/
https://www.ncbi.nlm.nih.gov/pubmed/35548189
http://dx.doi.org/10.3389/fsurg.2022.799669

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