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The Interplay Between Biliary Occlusion and Liver Regeneration: Repeated Regeneration Stimuli Restore Biliary Drainage by Promoting Hepatobiliary Remodeling in a Rat Model
BACKGROUND AND AIMS: Patients with malignant biliary obstruction do not seem to benefit from “two-stage hepatectomy” due to an impairment of liver regeneration. We designed a novel model of “repeated regeneration stimuli” in rats mimicking a “two-stage hepatectomy” with selective or complete biliary...
Autores principales: | Richter, Beate, Sänger, Constanze, Mussbach, Franziska, Scheuerlein, Hubert, Settmacher, Utz, Dahmen, Uta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081651/ https://www.ncbi.nlm.nih.gov/pubmed/35548189 http://dx.doi.org/10.3389/fsurg.2022.799669 |
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