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Multisystemic Sarcoidosis Revealed by Hepatosplenomegaly: A Case Report

Sarcoidosis is a systemic granulomatous disease of unknown etiology, characterized by the presence of non-caseating granulomas. Gastrointestinal involvement in sarcoidosis is extremely rare. However, hepatic sarcoidosis occurs in 70% of cases. This is a case report of multisystemic sarcoidosis revea...

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Autores principales: El Rhaoussi, Fatima Zahra, Banani, Soukaina, Bouamama, Sophia, Bennani, Nissrine, Badre, Wafaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081658/
https://www.ncbi.nlm.nih.gov/pubmed/35541289
http://dx.doi.org/10.7759/cureus.23967
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author El Rhaoussi, Fatima Zahra
Banani, Soukaina
Bouamama, Sophia
Bennani, Nissrine
Badre, Wafaa
author_facet El Rhaoussi, Fatima Zahra
Banani, Soukaina
Bouamama, Sophia
Bennani, Nissrine
Badre, Wafaa
author_sort El Rhaoussi, Fatima Zahra
collection PubMed
description Sarcoidosis is a systemic granulomatous disease of unknown etiology, characterized by the presence of non-caseating granulomas. Gastrointestinal involvement in sarcoidosis is extremely rare. However, hepatic sarcoidosis occurs in 70% of cases. This is a case report of multisystemic sarcoidosis revealed by hepatosplenomegaly. The patient presented initially with asthenia, anorexia, and weight loss. An abdominal computed tomography scan revealed hepatosplenomegaly and lumbo-aortic adenopathy. During hospitalization, the patient presented an extended erythematous cutaneous lesion in the peri-auricular area. The diagnosis of sarcoidosis was confirmed by salivary, cutaneous, and bronchoscopic biopsy, which revealed the presence of epithelioid granuloma without necrosis. Consequently, the patient was treated with oral corticosteroids with good improvement. 
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spelling pubmed-90816582022-05-09 Multisystemic Sarcoidosis Revealed by Hepatosplenomegaly: A Case Report El Rhaoussi, Fatima Zahra Banani, Soukaina Bouamama, Sophia Bennani, Nissrine Badre, Wafaa Cureus Internal Medicine Sarcoidosis is a systemic granulomatous disease of unknown etiology, characterized by the presence of non-caseating granulomas. Gastrointestinal involvement in sarcoidosis is extremely rare. However, hepatic sarcoidosis occurs in 70% of cases. This is a case report of multisystemic sarcoidosis revealed by hepatosplenomegaly. The patient presented initially with asthenia, anorexia, and weight loss. An abdominal computed tomography scan revealed hepatosplenomegaly and lumbo-aortic adenopathy. During hospitalization, the patient presented an extended erythematous cutaneous lesion in the peri-auricular area. The diagnosis of sarcoidosis was confirmed by salivary, cutaneous, and bronchoscopic biopsy, which revealed the presence of epithelioid granuloma without necrosis. Consequently, the patient was treated with oral corticosteroids with good improvement.  Cureus 2022-04-08 /pmc/articles/PMC9081658/ /pubmed/35541289 http://dx.doi.org/10.7759/cureus.23967 Text en Copyright © 2022, El Rhaoussi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
El Rhaoussi, Fatima Zahra
Banani, Soukaina
Bouamama, Sophia
Bennani, Nissrine
Badre, Wafaa
Multisystemic Sarcoidosis Revealed by Hepatosplenomegaly: A Case Report
title Multisystemic Sarcoidosis Revealed by Hepatosplenomegaly: A Case Report
title_full Multisystemic Sarcoidosis Revealed by Hepatosplenomegaly: A Case Report
title_fullStr Multisystemic Sarcoidosis Revealed by Hepatosplenomegaly: A Case Report
title_full_unstemmed Multisystemic Sarcoidosis Revealed by Hepatosplenomegaly: A Case Report
title_short Multisystemic Sarcoidosis Revealed by Hepatosplenomegaly: A Case Report
title_sort multisystemic sarcoidosis revealed by hepatosplenomegaly: a case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081658/
https://www.ncbi.nlm.nih.gov/pubmed/35541289
http://dx.doi.org/10.7759/cureus.23967
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