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Structural Basis for Allostery in PLP-dependent Enzymes

Pyridoxal 5′-phosphate (PLP)-dependent enzymes are found ubiquitously in nature and are involved in a variety of biological pathways, from natural product synthesis to amino acid and glucose metabolism. The first structure of a PLP-dependent enzyme was reported over 40 years ago, and since that time...

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Detalles Bibliográficos
Autores principales: Tran, Jenny U., Brown, Breann L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081730/
https://www.ncbi.nlm.nih.gov/pubmed/35547395
http://dx.doi.org/10.3389/fmolb.2022.884281