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Targeting GGT1 Eliminates the Tumor-Promoting Effect and Enhanced Immunosuppressive Function of Myeloid-Derived Suppressor Cells Caused by G-CSF

Myeloid-derived suppressor cells (MDSCs) are major immunosuppressive cells that accumulate in tumor-bearing hosts. Since MDSCs suppress anti-tumor immunity and promote tumor progression, they are promising targets for cancer immunotherapy. Granulocyte colony-stimulating factor (G-CSF) is an agent us...

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Detalles Bibliográficos
Autores principales: Xie, Zhiqi, Kawasaki, Takahiro, Zhou, Haoyang, Okuzaki, Daisuke, Okada, Naoki, Tachibana, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081766/
https://www.ncbi.nlm.nih.gov/pubmed/35548341
http://dx.doi.org/10.3389/fphar.2022.873792

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