Two decades of advances in diterpenoid alkaloids with cytotoxicity activities

The important pharmacological activities and structural complexity of diterpenoid alkaloids have long stimulated strong scientific interest; some of these naturally abundant compounds have been reported to be highly promising for treating cancer. From 2008 to 2018, the cytotoxicity activities of mor...

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Detalles Bibliográficos
Autores principales: Liang, Xiaoxia, Gao, Yingying, Luan, Shangxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081856/
https://www.ncbi.nlm.nih.gov/pubmed/35540251
http://dx.doi.org/10.1039/c8ra03911a
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author Liang, Xiaoxia
Gao, Yingying
Luan, Shangxian
author_facet Liang, Xiaoxia
Gao, Yingying
Luan, Shangxian
author_sort Liang, Xiaoxia
collection PubMed
description The important pharmacological activities and structural complexity of diterpenoid alkaloids have long stimulated strong scientific interest; some of these naturally abundant compounds have been reported to be highly promising for treating cancer. From 2008 to 2018, the cytotoxicity activities of more than 250 diterpenoid alkaloids were tested against several cancer cell lines. This review focuses on the progress of diterpenoid alkaloids with different structures derived from Ranunculaceae plants and some of their derivatives with potential anticancer activities. Then, we discuss the application prospects and development of active diterpenoid alkaloids.
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spelling pubmed-90818562022-05-09 Two decades of advances in diterpenoid alkaloids with cytotoxicity activities Liang, Xiaoxia Gao, Yingying Luan, Shangxian RSC Adv Chemistry The important pharmacological activities and structural complexity of diterpenoid alkaloids have long stimulated strong scientific interest; some of these naturally abundant compounds have been reported to be highly promising for treating cancer. From 2008 to 2018, the cytotoxicity activities of more than 250 diterpenoid alkaloids were tested against several cancer cell lines. This review focuses on the progress of diterpenoid alkaloids with different structures derived from Ranunculaceae plants and some of their derivatives with potential anticancer activities. Then, we discuss the application prospects and development of active diterpenoid alkaloids. The Royal Society of Chemistry 2018-07-02 /pmc/articles/PMC9081856/ /pubmed/35540251 http://dx.doi.org/10.1039/c8ra03911a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Liang, Xiaoxia
Gao, Yingying
Luan, Shangxian
Two decades of advances in diterpenoid alkaloids with cytotoxicity activities
title Two decades of advances in diterpenoid alkaloids with cytotoxicity activities
title_full Two decades of advances in diterpenoid alkaloids with cytotoxicity activities
title_fullStr Two decades of advances in diterpenoid alkaloids with cytotoxicity activities
title_full_unstemmed Two decades of advances in diterpenoid alkaloids with cytotoxicity activities
title_short Two decades of advances in diterpenoid alkaloids with cytotoxicity activities
title_sort two decades of advances in diterpenoid alkaloids with cytotoxicity activities
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081856/
https://www.ncbi.nlm.nih.gov/pubmed/35540251
http://dx.doi.org/10.1039/c8ra03911a
work_keys_str_mv AT liangxiaoxia twodecadesofadvancesinditerpenoidalkaloidswithcytotoxicityactivities
AT gaoyingying twodecadesofadvancesinditerpenoidalkaloidswithcytotoxicityactivities
AT luanshangxian twodecadesofadvancesinditerpenoidalkaloidswithcytotoxicityactivities

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