Risk of Lung Cancer and Occupational Exposure to Polycyclic Aromatic Hydrocarbons Among Workers Cohorts — Worldwide, 1969–2022

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Lung cancer has a high mortality, resulting in a severe disease burden. Polycyclic aromatic hydrocarbons (PAHs) are definitive carcinogen to human, and occupational exposure to PAHs is associated with lung cancer. WHAT IS ADDED BY THIS REPORT? We analyzed the...

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Detalles Bibliográficos
Autores principales: Yuan, Huige, Wang, Yanhua, Duan, Huawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2022
Materias:
Preplanned Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081899/
https://www.ncbi.nlm.nih.gov/pubmed/35547638
http://dx.doi.org/10.46234/ccdcw2022.085
Descripción
Sumario:WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Lung cancer has a high mortality, resulting in a severe disease burden. Polycyclic aromatic hydrocarbons (PAHs) are definitive carcinogen to human, and occupational exposure to PAHs is associated with lung cancer. WHAT IS ADDED BY THIS REPORT? We analyzed the cancer cases from cohort studies on various PAHs exposed workers in China and other countries, calculated the quantitative risk of lung cancer based on meta-analyses, and confirmed the increased risk from lung cancer in selected PAHs exposed occupations. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICES? There is a clear need to prevent lung cancer on a wide range of PAHs-related occupations in China and around the world. It is crucial to establish guidelines for improving the monitoring on exposure and health promotion in related working environments.

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