The HSP40 chaperone Ydj1 drives amyloid beta 42 toxicity

Amyloid beta 42 (Abeta42) is the principal trigger of neurodegeneration during Alzheimer’s disease (AD). However, the etiology of its noxious cellular effects remains elusive. In a combinatory genetic and proteomic approach using a yeast model to study aspects of intracellular Abeta42 toxicity, we h...

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Detalles Bibliográficos
Autores principales: Ring, Julia, Tadic, Jelena, Ristic, Selena, Poglitsch, Michael, Bergmann, Martina, Radic, Nemanja, Mossmann, Dirk, Liang, YongTian, Maglione, Marta, Jerkovic, Andrea, Hajiraissi, Roozbeh, Hanke, Marcel, Küttner, Victoria, Wolinski, Heimo, Zimmermann, Andreas, Domuz Trifunović, Lana, Mikolasch, Leonie, Moretti, Daiana N, Broeskamp, Filomena, Westermayer, Julia, Abraham, Claudia, Schauer, Simon, Dammbrueck, Christopher, Hofer, Sebastian J, Abdellatif, Mahmoud, Grundmeier, Guido, Kroemer, Guido, Braun, Ralf J, Hansen, Niklas, Sommer, Cornelia, Ninkovic, Mirjana, Seba, Sandra, Rockenfeller, Patrick, Vögtle, Friederike‐Nora, Dengjel, Jörn, Meisinger, Chris, Keller, Adrian, Sigrist, Stephan J, Eisenberg, Tobias, Madeo, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081910/
https://www.ncbi.nlm.nih.gov/pubmed/35373908
http://dx.doi.org/10.15252/emmm.202113952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9081910/
https://www.ncbi.nlm.nih.gov/pubmed/35373908
http://dx.doi.org/10.15252/emmm.202113952

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