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Coexisting Choroidal and Brain Metastases in a Patient with Breast Cancer Treated with Stereotactic Radiotherapy

Choroidal metastases from breast cancer are the most common ocular malignancies in adults. We report a case of a 37-year-old female with a history of breast cancer who had a sudden blurred vision in her right eye. An ophthalmologic assessment revealed a dome-shaped lesion and a secondary retinal det...

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Autores principales: Oliverio, Giovanni William, Tedesco, Giovanni Roberto, Azzaro, Claudia, Meduri, Alessandro, Aragona, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082143/
https://www.ncbi.nlm.nih.gov/pubmed/35611014
http://dx.doi.org/10.1159/000523732
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author Oliverio, Giovanni William
Tedesco, Giovanni Roberto
Azzaro, Claudia
Meduri, Alessandro
Aragona, Pasquale
author_facet Oliverio, Giovanni William
Tedesco, Giovanni Roberto
Azzaro, Claudia
Meduri, Alessandro
Aragona, Pasquale
author_sort Oliverio, Giovanni William
collection PubMed
description Choroidal metastases from breast cancer are the most common ocular malignancies in adults. We report a case of a 37-year-old female with a history of breast cancer who had a sudden blurred vision in her right eye. An ophthalmologic assessment revealed a dome-shaped lesion and a secondary retinal detachment with subretinal fluid in the left eye, suggestive of choroidal metastasis. Moreover, an MRI scan showed the presence of a single brain lesion. The patient was treated with stereotactic radiotherapy, with 300 cGy for 10 days. Six months after treatment, there was a regression of the mass and improvement of visual acuity. Stereotactic radiotherapy is a safe and effective treatment for choroidal metastases and should be considered to treat coexistent choroidal and brain metastatic lesions, to improve survival, visual function, and quality of life.
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spelling pubmed-90821432022-05-23 Coexisting Choroidal and Brain Metastases in a Patient with Breast Cancer Treated with Stereotactic Radiotherapy Oliverio, Giovanni William Tedesco, Giovanni Roberto Azzaro, Claudia Meduri, Alessandro Aragona, Pasquale Case Rep Ophthalmol Case Report Choroidal metastases from breast cancer are the most common ocular malignancies in adults. We report a case of a 37-year-old female with a history of breast cancer who had a sudden blurred vision in her right eye. An ophthalmologic assessment revealed a dome-shaped lesion and a secondary retinal detachment with subretinal fluid in the left eye, suggestive of choroidal metastasis. Moreover, an MRI scan showed the presence of a single brain lesion. The patient was treated with stereotactic radiotherapy, with 300 cGy for 10 days. Six months after treatment, there was a regression of the mass and improvement of visual acuity. Stereotactic radiotherapy is a safe and effective treatment for choroidal metastases and should be considered to treat coexistent choroidal and brain metastatic lesions, to improve survival, visual function, and quality of life. S. Karger AG 2022-03-21 /pmc/articles/PMC9082143/ /pubmed/35611014 http://dx.doi.org/10.1159/000523732 Text en Copyright © 2022 by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Oliverio, Giovanni William
Tedesco, Giovanni Roberto
Azzaro, Claudia
Meduri, Alessandro
Aragona, Pasquale
Coexisting Choroidal and Brain Metastases in a Patient with Breast Cancer Treated with Stereotactic Radiotherapy
title Coexisting Choroidal and Brain Metastases in a Patient with Breast Cancer Treated with Stereotactic Radiotherapy
title_full Coexisting Choroidal and Brain Metastases in a Patient with Breast Cancer Treated with Stereotactic Radiotherapy
title_fullStr Coexisting Choroidal and Brain Metastases in a Patient with Breast Cancer Treated with Stereotactic Radiotherapy
title_full_unstemmed Coexisting Choroidal and Brain Metastases in a Patient with Breast Cancer Treated with Stereotactic Radiotherapy
title_short Coexisting Choroidal and Brain Metastases in a Patient with Breast Cancer Treated with Stereotactic Radiotherapy
title_sort coexisting choroidal and brain metastases in a patient with breast cancer treated with stereotactic radiotherapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082143/
https://www.ncbi.nlm.nih.gov/pubmed/35611014
http://dx.doi.org/10.1159/000523732
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