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Insights into the interaction mechanism between tiagabine hydrochloride and two serum albumins

Tiagabine hydrochloride (TGB) is a widely used anticonvulsive drug for the treatment of epilepsy. To better understand the interactions of TGB with plasma proteins, human serum albumin (HSA) and bovine serum albumin (BSA) were selected as model proteins. TGB slightly increased thermal stability of t...

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Detalles Bibliográficos
Autores principales: Zhuo, Weiling, Peng, Xilin, Lin, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082336/
https://www.ncbi.nlm.nih.gov/pubmed/35542170
http://dx.doi.org/10.1039/c8ra04153a