Importance of Linear Combination Modeling for Quantification of Glutathione and γ-Aminobutyric Acid Levels Using Hadamard-Edited Magnetic Resonance Spectroscopy

BACKGROUND: J-difference-edited (1)H-MR spectra require modeling to quantify signals of low-concentration metabolites. Two main approaches are used for this spectral modeling: simple peak fitting and linear combination modeling (LCM) with a simulated basis set. Recent consensus recommended LCM as th...

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Detalles Bibliográficos
Autores principales: Song, Yulu, Zöllner, Helge J., Hui, Steve C. N., Hupfeld, Kathleen, Oeltzschner, Georg, Prisciandaro, James J., Edden, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082488/
https://www.ncbi.nlm.nih.gov/pubmed/35546940
http://dx.doi.org/10.3389/fpsyt.2022.872403

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