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P1c peptide decorated liposome targeting αvβ3-expressing tumor cells in vitro and in vivo

Integrin αvβ3 is a promising target for integrin-rich tumor and neovascular. In the present study, we prepared a doxorubicin (DOX)-loaded liposome of which the surface was decorated with PEG and a novel αvβ3 targeting peptide of P1c. The in vitro targeting efficiency was evaluated in αvβ3-positive (...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Yan, Xuejiao, Liu, Naifeng, Wu, Guoqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082570/
https://www.ncbi.nlm.nih.gov/pubmed/35539761
http://dx.doi.org/10.1039/c8ra05014g