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High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition

In support of the Endocrine Disruptor Screening Program (EDSP), the U.S.EPA's Office of Research and Development (ORD) is developing high-throughput screening (HTS) approaches to identify chemicals that alter target sites in the thyroid hormone (TH) pathway. The sodium iodide symporter (NIS) is...

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Detalles Bibliográficos
Autores principales:	Wang, Jun, Hallinger, Daniel R., Murr, Ashley S., Buckalew, Angela R., Lougee, Ryan R., Richard, Ann M., Laws, Susan C., Stoker, Tammy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082575/ https://www.ncbi.nlm.nih.gov/pubmed/30826616 http://dx.doi.org/10.1016/j.envint.2019.02.024

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