The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease

The leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of...

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Autores principales: Inczefi, Orsolya, Bacsur, Péter, Resál, Tamás, Keresztes, Csilla, Molnár, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082752/
https://www.ncbi.nlm.nih.gov/pubmed/35548572
http://dx.doi.org/10.3389/fnut.2022.718710
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author Inczefi, Orsolya
Bacsur, Péter
Resál, Tamás
Keresztes, Csilla
Molnár, Tamás
author_facet Inczefi, Orsolya
Bacsur, Péter
Resál, Tamás
Keresztes, Csilla
Molnár, Tamás
author_sort Inczefi, Orsolya
collection PubMed
description The leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of cancer, and neuropsychiatric disorders. In this study, the mechanisms leading to dysbiosis and “leaky gut” are reviewed, and a short summary of the current knowledge regarding different diseases is provided. The simplest way to restore intestinal permeability and the microbiota could be ideal nutrition. Further therapeutic options are also available, such as the administration of probiotics or postbiotics or fecal microbiota transplantation.
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spelling pubmed-90827522022-05-10 The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease Inczefi, Orsolya Bacsur, Péter Resál, Tamás Keresztes, Csilla Molnár, Tamás Front Nutr Nutrition The leakage of the intestinal barrier and the disruption of the gut microbiome are increasingly recognized as key factors in different pathophysiological conditions, such as irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), chronic liver diseases, obesity, diabetes mellitus, types of cancer, and neuropsychiatric disorders. In this study, the mechanisms leading to dysbiosis and “leaky gut” are reviewed, and a short summary of the current knowledge regarding different diseases is provided. The simplest way to restore intestinal permeability and the microbiota could be ideal nutrition. Further therapeutic options are also available, such as the administration of probiotics or postbiotics or fecal microbiota transplantation. Frontiers Media S.A. 2022-04-25 /pmc/articles/PMC9082752/ /pubmed/35548572 http://dx.doi.org/10.3389/fnut.2022.718710 Text en Copyright © 2022 Inczefi, Bacsur, Resál, Keresztes and Molnár. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Inczefi, Orsolya
Bacsur, Péter
Resál, Tamás
Keresztes, Csilla
Molnár, Tamás
The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease
title The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease
title_full The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease
title_fullStr The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease
title_full_unstemmed The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease
title_short The Influence of Nutrition on Intestinal Permeability and the Microbiome in Health and Disease
title_sort influence of nutrition on intestinal permeability and the microbiome in health and disease
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082752/
https://www.ncbi.nlm.nih.gov/pubmed/35548572
http://dx.doi.org/10.3389/fnut.2022.718710
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