Coding joint: kappa-deleting recombination excision circle ratio and B cell activating factor level: predicting juvenile dermatomyositis rituximab response, a proof-of-concept study

BACKGROUND: This pilot study’s primary aim was to determine if oligoclonal B cell expansion in children with Juvenile Dermatomyositis (JDM) predicts response to Rituximab therapy. We evaluated: (1) tissue B cell depletion efficacy by measuring the ratio of Coding joint (CJ) to Kappa-deleting recombi...

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Detalles Bibliográficos
Autores principales: Ochfeld, Elisa, Hans, Victoria, Marin, Wil, Ahsan, Najah, Morgan, Gabrielle, Pachman, Lauren M., Khojah, Amer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082850/
https://www.ncbi.nlm.nih.gov/pubmed/35527253
http://dx.doi.org/10.1186/s41927-022-00265-z

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