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Cytotoxic effect of disulfiram/copper on human cervical cancer cell lines and LGR5-positive cancer stem-like cells

BACKGROUND: Tumor resistance is a global challenge for tumor treatment. Cancer stem cells (CSCs) are the main population of tumor cells for drug resistance. We have reported that high aldehyde dehydrogenase (ALDH) activity represents a functional marker for cervical CSCs. Here, we aimed at disulfira...

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Detalles Bibliográficos
Autores principales: Cao, Hao-Zhe, Yang, Wen-Ting, Zheng, Peng-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082913/
https://www.ncbi.nlm.nih.gov/pubmed/35534815
http://dx.doi.org/10.1186/s12885-022-09574-5