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Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome

OBJECTIVE: Polycystic ovary syndrome (PCOS) is characterized by follicular dysplasia. An insufficient glycolysis-derived energy supply of granulosa cells (GCs) is an important cause of follicular dysplasia in PCOS. Follicular fluid (FF) exosomal microRNAs (miRNAs) have been proven to regulate the fu...

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Detalles Bibliográficos
Autores principales: Cao, Jianping, Huo, Peng, Cui, Kuiqing, Wei, Huimei, Cao, Junna, Wang, Jinyuan, Liu, Qingyou, Lei, Xiaocan, Zhang, Shun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9082924/
https://www.ncbi.nlm.nih.gov/pubmed/35534864
http://dx.doi.org/10.1186/s12964-022-00876-6