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Synthesis and evaluation of new sterol derivatives as potential antitumor agents

The current optimization of tetrazanbigen (TNBG) on the C-ring provided a series of new sterol derivatives 2a–2n. All new synthesized compounds were screened for their anti-proliferation activities against five human cancer cell lines (HepG2, QGY-7701, SMMC-7721, A-431 and NCI-H23 cell lines) in vit...

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Detalles Bibliográficos
Autores principales: Chen, Xiang, Gan, Yong Jun, Yu, Yu, Zhang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083030/
https://www.ncbi.nlm.nih.gov/pubmed/35541052
http://dx.doi.org/10.1039/c8ra04152k