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Synthesis and evaluation of new sterol derivatives as potential antitumor agents
The current optimization of tetrazanbigen (TNBG) on the C-ring provided a series of new sterol derivatives 2a–2n. All new synthesized compounds were screened for their anti-proliferation activities against five human cancer cell lines (HepG2, QGY-7701, SMMC-7721, A-431 and NCI-H23 cell lines) in vit...
Autores principales: | Chen, Xiang, Gan, Yong Jun, Yu, Yu, Zhang, Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083030/ https://www.ncbi.nlm.nih.gov/pubmed/35541052 http://dx.doi.org/10.1039/c8ra04152k |
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