Copper-catalyzed C–S direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester

A selective copper (Cu)-catalyzed C–S bond direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester was developed. Notably, various biologically active 5-phenyl-3-phenylsulfanylpenta-2,4-dienoic acid ethyl ester derivatives were efficiently synthesized under moderate conditions....

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Detalles Bibliográficos
Autores principales: Cai, Rongrong, Zhou, Zhuoda, Chai, Qianqian, Zhu, Yueer, Xu, Runsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083087/
https://www.ncbi.nlm.nih.gov/pubmed/35541071
http://dx.doi.org/10.1039/c8ra05311a
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author Cai, Rongrong
Zhou, Zhuoda
Chai, Qianqian
Zhu, Yueer
Xu, Runsheng
author_facet Cai, Rongrong
Zhou, Zhuoda
Chai, Qianqian
Zhu, Yueer
Xu, Runsheng
author_sort Cai, Rongrong
collection PubMed
description A selective copper (Cu)-catalyzed C–S bond direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester was developed. Notably, various biologically active 5-phenyl-3-phenylsulfanylpenta-2,4-dienoic acid ethyl ester derivatives were efficiently synthesized under moderate conditions. Finally, a plausible Cu(i)/Cu(iii) reaction mechanism was proposed.
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spelling pubmed-90830872022-05-09 Copper-catalyzed C–S direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester Cai, Rongrong Zhou, Zhuoda Chai, Qianqian Zhu, Yueer Xu, Runsheng RSC Adv Chemistry A selective copper (Cu)-catalyzed C–S bond direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester was developed. Notably, various biologically active 5-phenyl-3-phenylsulfanylpenta-2,4-dienoic acid ethyl ester derivatives were efficiently synthesized under moderate conditions. Finally, a plausible Cu(i)/Cu(iii) reaction mechanism was proposed. The Royal Society of Chemistry 2018-07-27 /pmc/articles/PMC9083087/ /pubmed/35541071 http://dx.doi.org/10.1039/c8ra05311a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Cai, Rongrong
Zhou, Zhuoda
Chai, Qianqian
Zhu, Yueer
Xu, Runsheng
Copper-catalyzed C–S direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester
title Copper-catalyzed C–S direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester
title_full Copper-catalyzed C–S direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester
title_fullStr Copper-catalyzed C–S direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester
title_full_unstemmed Copper-catalyzed C–S direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester
title_short Copper-catalyzed C–S direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester
title_sort copper-catalyzed c–s direct cross-coupling of thiols with 5-arylpenta-2,4-dienoic acid ethyl ester
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083087/
https://www.ncbi.nlm.nih.gov/pubmed/35541071
http://dx.doi.org/10.1039/c8ra05311a
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