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Toxicities of amyloid-beta and tau protein are reciprocally enhanced in the Drosophila model
Extracellular aggregation of amyloid-beta (Aβ) and intracellular tau tangles are two major pathogenic hallmarks and critical factors of Alzheimer’s disease. A linear interaction between Aβ and tau protein has been characterized in several models. Aβ induces tau hyperphosphorylation through a complex...
Autores principales: | Sun, Zhen-Dong, Hu, Jia-Xin, Wu, Jia-Rui, Zhou, Bing, Huang, Yun-Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083152/ https://www.ncbi.nlm.nih.gov/pubmed/35259851 http://dx.doi.org/10.4103/1673-5374.336872 |
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