Fractional optimal control of compartmental SIR model of COVID-19: Showing the impact of effective vaccination

In this work a compartmental SIR model has been proposed for describing the dynamics of COVID-19 with Caputo’s fractional derivative(FD). SIR compartmental model has been used here with fractional differential equations(FDEs). The mathematical model of the pandemic consists of three compartments namely susceptible, infected and recovered individuals. The dynamics of the pandemic COVID-19 with FDEs for showing the effect of memory as most of the cell biological systems can be described accurately by FDEs Time dependent control(Effective vaccination) has been applied model to formulated fractional optimal control problem(FOCP) to reduce the viral load. Pontryagin’s Maximum Principle(PMP) has been used to formulate FOCP. An effective vaccination is very helpful for controlling the pandemic, which is observed through the numerical simulation via Grunwald-Letnikov(G-L) approximation. All numerical simulation work has been carried in MATLAB platform.