Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy

Immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients with malignant disease may be affected by tumor therapy. Here, we report the case of a child with rhabdomyosarcoma and recurrent SARS-CoV-2 infection. Immunologic responses, analyzed by T...

Descripción completa

Detalles Bibliográficos
Autores principales: Eichholz, Thomas, Arendt, Anne-Marie, Holzer, Ursula, Seitz, Christian, Rabsteyn, Armin, Ganzenmueller, Tina, Klein, Reinhild, Walz, Juliane, Lang, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Immunology and Host Response
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083311/
https://www.ncbi.nlm.nih.gov/pubmed/35446806
http://dx.doi.org/10.1097/INF.0000000000003515
_version_ 1784703394698493952
author Eichholz, Thomas
Arendt, Anne-Marie
Holzer, Ursula
Seitz, Christian
Rabsteyn, Armin
Ganzenmueller, Tina
Klein, Reinhild
Walz, Juliane
Lang, Peter
author_facet Eichholz, Thomas
Arendt, Anne-Marie
Holzer, Ursula
Seitz, Christian
Rabsteyn, Armin
Ganzenmueller, Tina
Klein, Reinhild
Walz, Juliane
Lang, Peter
author_sort Eichholz, Thomas
collection PubMed
description Immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients with malignant disease may be affected by tumor therapy. Here, we report the case of a child with rhabdomyosarcoma and recurrent SARS-CoV-2 infection. Immunologic responses, analyzed by T-cell activity and anti-viral IgG levels, were impaired and not durable as a result of intensive radiochemotherapy.
format Online
Article
Text
id pubmed-9083311
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-90833112022-05-11 Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy Eichholz, Thomas Arendt, Anne-Marie Holzer, Ursula Seitz, Christian Rabsteyn, Armin Ganzenmueller, Tina Klein, Reinhild Walz, Juliane Lang, Peter Pediatr Infect Dis J Immunology and Host Response Immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients with malignant disease may be affected by tumor therapy. Here, we report the case of a child with rhabdomyosarcoma and recurrent SARS-CoV-2 infection. Immunologic responses, analyzed by T-cell activity and anti-viral IgG levels, were impaired and not durable as a result of intensive radiochemotherapy. Lippincott Williams & Wilkins 2022-05-06 2022-06 /pmc/articles/PMC9083311/ /pubmed/35446806 http://dx.doi.org/10.1097/INF.0000000000003515 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal
spellingShingle Immunology and Host Response
Eichholz, Thomas
Arendt, Anne-Marie
Holzer, Ursula
Seitz, Christian
Rabsteyn, Armin
Ganzenmueller, Tina
Klein, Reinhild
Walz, Juliane
Lang, Peter
Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy
title Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy
title_full Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy
title_fullStr Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy
title_full_unstemmed Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy
title_short Recurrent SARS-CoV-2 Infection and Impaired Immunologic Response in a Pediatric Oncologic Patient While Treated With Radiochemotherapy
title_sort recurrent sars-cov-2 infection and impaired immunologic response in a pediatric oncologic patient while treated with radiochemotherapy
topic Immunology and Host Response
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083311/
https://www.ncbi.nlm.nih.gov/pubmed/35446806
http://dx.doi.org/10.1097/INF.0000000000003515
work_keys_str_mv AT eichholzthomas recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy
AT arendtannemarie recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy
AT holzerursula recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy
AT seitzchristian recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy
AT rabsteynarmin recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy
AT ganzenmuellertina recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy
AT kleinreinhild recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy
AT walzjuliane recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy
AT langpeter recurrentsarscov2infectionandimpairedimmunologicresponseinapediatriconcologicpatientwhiletreatedwithradiochemotherapy

Ejemplares similares