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Impact of ABCB1 Polymorphisms on Lacosamide Serum Concentrations in Uygur Pediatric Patients With Epilepsy in China

P-glycoprotein, encoded by ABCB1 (or MDR1), may contribute to drug resistance in epilepsy by limiting gastrointestinal absorption and brain access to antiseizure medications. The study aimed to evaluate the impact of ABCB1 polymorphisms on lacosamide (LCM) serum concentrations in Uygur pediatric pat...

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Detalles Bibliográficos
Autores principales:	Zhao, Ting, Li, Hong-jian, Feng, Jie, Zhang, Hui-lan, Ting-ting, Wang, Ma, Long, Yu, Jing, Zhao, Wen-bo, Sun, Li, Yu, Lu-hai, Sun, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Therapeutic Drug Monitoring 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083488/ https://www.ncbi.nlm.nih.gov/pubmed/34610620 http://dx.doi.org/10.1097/FTD.0000000000000927

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