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Chronic activation of MUC1-C in wound repair promotes progression to cancer stem cells
The mucin 1 (MUC1) gene emerged in mammals to afford protection of barrier epithelial tissues from the external environment. MUC1 encodes a transmembrane C-terminal (MUC1-C) subunit that is activated by loss of homeostasis and induces inflammatory, proliferative, and remodeling pathways associated w...
Autor principal: | Kufe, Donald W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083497/ https://www.ncbi.nlm.nih.gov/pubmed/35539431 http://dx.doi.org/10.20517/2394-4722.2022.03 |
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