Different Mechanisms of DNA Radiosensitization by 8-Bromoadenosine and 2′-Deoxy-2′-fluorocytidine Observed on DNA Origami Nanoframe Supports

[Image: see text] DNA origami nanoframes with two parallel DNA sequences are used to evaluate the effect of nucleoside substituents on radiation-induced DNA damage. Double strand breaks (DSB) of DNA are counted using atomic force microscopy (AFM), and total number of lesions is evaluated using real-...

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Detalles Bibliográficos
Autores principales: Sala, Leo, Lyshchuk, Hlib, Šáchová, Jana, Chvátil, David, Kočišek, Jaroslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083549/
https://www.ncbi.nlm.nih.gov/pubmed/35472278
http://dx.doi.org/10.1021/acs.jpclett.2c00584

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