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Plasma neurofilament light in Huntington’s disease: A marker for disease onset, but not symptom progression
OBJECTIVE: To investigate whether plasma NfL levels correlate with clinical symptom severity in premanifest (PM) and manifest HD (HD) individuals, and whether a NfL cut-point could distinguish PM from HD patients with reasonable accuracy. METHOD: 98 participants (33 control, 26 PM, 39 HD), underwent...
Autores principales: | Parkin, Georgia M., Corey-Bloom, Jody, Snell, Chase, Castleton, Jordan, Thomas, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083556/ https://www.ncbi.nlm.nih.gov/pubmed/33940564 http://dx.doi.org/10.1016/j.parkreldis.2021.04.017 |
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