Pure white cell aplasia an exceptional condition in the immunological conundrum of thymomas: Responses to immunosuppression and literature review

Thymomas are tumours frequently associated with autoimmune manifestations or immunodeficiencies like Good syndrome. In rare cases, pure white cells aplasia (PWCA) has been described in association with thymomas. PWCA is characterized by agranulocytosis of autoimmune background primary refractory to...

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Detalles Bibliográficos
Autores principales: Céspedes López, Roberto, Amutio Díez, Elena, Martín Martitegui, Xabier, Balerdi Malcorra, Amaia, Insunza Oleaga, Lucia, Arzuaga‐Méndez, Javier, Moreno Gámiz, Maite, Saiz Camín, Mónica, Aberasturi Plata, Yoseba, García‐Ruíz, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9083807/
https://www.ncbi.nlm.nih.gov/pubmed/35582161
http://dx.doi.org/10.1002/ccr3.5742
Descripción
Sumario:Thymomas are tumours frequently associated with autoimmune manifestations or immunodeficiencies like Good syndrome. In rare cases, pure white cells aplasia (PWCA) has been described in association with thymomas. PWCA is characterized by agranulocytosis of autoimmune background primary refractory to granulocyte colony‐stimulating factor (G‐CSF). It is necessary the use of immunosuppressor to allow granulocyte recovery. Without treatment, it could be fatal.

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